The antimicrobial activity of the nhexane, methanol and. Download complete, reliable and ready made biochemistry project work. The effects of methanol extract of buchholzia coriacea seed was studied on male reproductive system of albino rats. Phytochemical and nutritive quality of dried seeds of buchholzia coriacea 1ibrahim t. Evidences abound for its diverse medicinal potentials. The ethanol extract of buchholzia coriacea is administered to ovalbumin. The hypoglycemic and antioxidant effects of the methanolic extract of buchholzia coriacea fruits in streptozotocininduced diabetic rats were investigated.
Seeds of buchholzia coriacea in diet mitigate ischemic. Journal of developmental biology and tissue engineering. However, study to demonstrate its involvement in t2d experimental. Pdf buchholzia coriacea wonderful cola, belonging to the family of capparidaceae is an evergreen shrub, which is distributed in cameroon. Type of buchholzia macrophylla pax family capparaceae on. Contribution to ethno botanical and floristic studies in.
Medicinal potentials of buchholzia coriacea wonderful. Iita headquarters pmb 5320, oyo road, ibadan 200001, oyo state, nigeria. Buchholzia coriacea bc, commonly known as wonderful kola, is a perennial plant which grows as a tree. Notably, it is a referred, highly indexed, online international journal with high impact factor. Antiinflammatory activity of buchholzia coriacea engl. Antidepressantlike potentials of buchholzia coriacea seed. This study investigated the phytochemical content, proximate analysis, acute toxicity test, antimicrobial, and antiinflammatory effect of buchholzia coriacea wonderful kola seed fractions using standard methods. Intestinal handling of glucose in buccholzia coriacea. Structural and functional properties of buchholzia. Buchholzia coriacea, taken by elderly, has phytochemicals that have neuroactive metabolites, and the folklore documented its use in neurobehavioral despairs. The qualitative phytochemical analysis of water and methanolic extracts of dried seed of buchholzia coriacea, proximate composition and mineral contents of raw, cooked and dried seed samples were determined using standard methods.
Previous study in our laboratory shows that methanol extracts of buchholzia coriacea mebc seeds possess antidepressantlike potentials in laboratory rodents. Medicinal potentials of buchholzia coriacea wonderful kola wonderful kola buchholzia coriacea is geographically distributed in some africa countries. Buchholzia coriacea engle capparidaceae known as musk tree 6 is found mostly in guinea, west cameroon, east cameroon and gabon 7. The chloroform extract was the most active with an average mic value of 1. The results of the antifungal assay are shown in table iv. It belongs to the family capparidaceae and genus buchholzia. Preliminary study on the effects of buchholzia coriacea seed extract. The methanol extract of buchholzia coriacea seeds did not show any antitrypanosomal activity in mice infected with. Ep1727519b1 cosmetic and pharmaceutical uses of an. The effect of ethanolic extract of buchholzia coriacea eebc on the lipid profile levels and extent of lipid peroxidation in hypercholesterolemic albino rats was.
The buchholzia coriacea seeds capparaceae are used in nigerian ethnomedicine for treatment of. Antidiabetic property and phytochemical composition of aqueous and methanol extracts of buchholzia coriacea seeds in alloxaninduced diabetic rats. Applications of fluorescence in situ hybridization in detection of disease biomarkers and personalized medicine. Fractions prepared from the methanol extract of buchholzia coriacea stem bark exhibited a high concentrationdependent antibacterial and antifungal activity. To investigate the effect of oral administration of buchholzia coriacea aqueous seed extract on blood glucose and other biochemical parameters in alloxaninduced diabetic rats and in normal. Analgesic and antiinflammatory effects of ethanol extracts of. It is a tree characterized with a dense brown, large glossy leathery leaves arranged spirally and with conspicuous creamwhite flowers. The antimicrobial activity of the nhexane, methanol and aqueous extracts of b. Essential oil and fatty acid constituents of buccholzia coriacea. Essential oil and fatty acid constituents of buccholzia.
Immunomodulatory activity of buchholzia coriacea seed. Read antiinflammatory activity of buchholzia coriacea engl. Download the complete biochemistry topic and material chapter 15 titled modulation of high fructose fed, streptozotocininduced type 2 diabetes by wonderful kola buchholzia coriacea seed extracts in male wistar rats here on projects. Investigation of the antitrypanosomal activity of buchholzia coriacea seed extract against a field strain of trypanosoma congolense 1nweze, n. Access is allocated within two business days of purchase and lasts one year. Get new biochemistry project ideas or search for related biochemistry projects using our search box for nd, hnd, bsc, msc, pgd, phd. Its use in folklore medicine is popular for diabetes.
Fractions prepared from the methanol extract of buchholzia coriacea stem bark exhibited a high concentrationdependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. Antimicrobial and cytotoxicity evaluation of buchholzia. See status, confidence level, source for definitions. Comparative clinical pathology, volume 28, issue 1 springer.
Antihypercholesterolemic activity of ethanolic extract of buchholzia. Anthelmintic activities of chloroform and methanol. Pdf the effect of aqueous extract of buchholzia coriacea. Studies on the antioxidant and antimicrobial activities of. International journal of science and research ijsr is published as a monthly journal with 12 issues per year. At doses of 10 mgkg, 25 mgkg and 50 mgkg, the extracts were tested against eudrilus eugeniae earthworm and bunostomum. Pdf investigation of the antitrypanosomal activity of. In the brine shrimp lethality bsl assay, the methanol extract was found to be nontoxic with an lc 50 of 1031. In this study, the possible mechanisms by which these seeds induce male reproductive toxicity were examined. It showed staphylococcus aureus was the most susceptible while bacillus cereus was the least.
From the results 1,2benzenedicarboxylic acid, mono 2ethylhexyl ester 74. Treatment with 150, 300 and 600 mg kg1 of the extract induced significant p download pdf. Buchholzia coriacea seeds have been reported to induce reproductive toxicity. See below for the abstract, table of contents, list of figures, list of tables, list of appendices, list of abbreviations and chapter one. This work determined the physicochemical and functional properties of a seed flour wcf and its protein concentrate wcc, prepared from the underutilized wonderful cola buchholzia coriacea seeds. The qualitative, quantitative phytochemical analyses, proximate and the minerals composition of dried seeds of buchholzia coriacea were determined using. Phytochemical and chemical properties of raw, cooked and. Read hypoglycemic activity of buchholzia coriacea capparaceae seeds in streptozotocininduced diabetic rats and mice, experimental and toxicologic pathology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at. Thirty male wistar rats, weighing between 100 120 g were used and randomly assigned into three groups of 5 rats each per. Antimicrobial and cytotoxicity evaluation of buchholzia coriacea.
List of biochemistry project topics in pdf and word. Hypoglycemic activity of buchholzia coriacea capparaceae. Analgesic effect of the extract was assessed using the formalininduced paw. African crocus curculigo pilosa and wonderful kola buchholzia coriacea seeds modulate critical enzymes relevant to erectile dysfunction and oxidative stress. Pdf african crocus curculigo pilosa and wonderful kola. Antimicrobial, antiinflammatory, and chemical evaluation.
Data from this study uncovered the presence of sixteen essential oils and ten fatty acids. Biochemistry project topics and materials projectng. Chemoprotective effects of butanol fraction of buchholzia. The methanol extract of buchholzia coriacea seeds did not show any antitrypanosomal activity in mice infected with trypanosoma congolense at the doses tested. The seeds of buchholzia coriacea engler capparaceae are used in eastern nigeria to treat feverish conditions, and to treat malaria and sleeping sickness that cause fever. By the end of the experiment, a 50 % relapse rate was recorded in the diminazene diaceturatetreated group. The antibacterial efficacy of hot water and methanol extracts of dried seeds of buchholzia coriacea against escherichia coli, staphylococcus aureus, salmonella typhimurium, bacillus cereus, and vibrio cholerae were determined using the agargel diffusion method. The seeds of buchholzia coriacea engler capparaceae are used in eastern nigeria to treat feverish conditions, and to treat malaria. The genus buchholzia is in the family capparaceae in the major group angiosperms flowering plants.
Antioxidant and anti hypertensive activities of wonderful cola buchholzia coriacea seed protein and enzymatic protein hydrolysates. Methanol fraction mfbc50 and 100 mgkg, hexane fraction hfbc50 mgkg or ethylacetate fraction efbc50 mgkg of b. The anthelmintic potentials of the chloroform and methanol extracts of buchholzia coriacea engler seed were investigated. Phytochemical and nutritive qualities of dried seeds of buchholzia. Buchholzia in kew science plants of the world online. Effects of seed fractions of buchholzia coriacea on. The current study assesses the immunomodulatory activity of buchholzia coriacea seed extract on trypanosoma brucei brucei infected mice. Its role in intestinal glucose uptake was investigated. Alternatively, you can download the pdf file directly to your computer, from where it can be opened using a pdf reader. The present study evaluates the possible hypoglycemic activity and ameliorative effects of oral administration of ethanol extracts eebc and butanol fraction bfbc of buchholzia coriacea seeds, a plant in use traditionally for treating diabetes, hypertension, rheumatism, cold, cough and catarrh, in streptozotocin stzinduced diabetic mice and rats. To download the pdf, click the download link above. Male wistar rats 150200 g were divided into 7 groups n 15. The antiplasmodial activity of buchholzia coriacea okoli, b. Buchholzia coriacea capparidacea is used in traditional medicine in the congo basin to alleviate common ailments including inflammatory diseases, asthma, pain, fever, wounds, abscesses.
It was tolerated up to dose of 2000 mg kg1 orally in rats. For the methanol extract, 12 animals were divided into 4 groups of 3 rats. Phytochemical and nutritive quality of dried seeds of. Comparative hypolipidaemic effects of crude seed powder, aqueous and methanolic seed extracts of buchholzia coriacea in carbon tetrachlorideinduced toxicity in albino rats rattus. Buchholzia coriacea seeds at 50mgkg, 100mgkg and 200mgkg respectively. Antibacterial and antifungal activities of ethanolic and. Effects of methanol extract of buchholzia coriacea fruit. Different studies have unveiled the traditional usefulness and clinical potentials of buchholzia coriacea, a medicinal plant known for its effectiveness in lowering blood glucose. Pdf antimicrobial and antihelmintic effect of wonderful. Antimicrobial, antiinflammatory, and chemical evaluation of buchholzia coriacea seed wonderful kola. Pdf antidiabetic property and phytochemical composition. Pdf antioxidant and anti hypertensive activities of. Request pdf on jan 1, 2018, sylvester chibueze izah and others published medicinal potentials of buchholzia coriacea wonderful kola find, read and cite all the research you need on researchgate.
To clarify this, the gastrohealing activities were investigated using graded incorporation of b. Investigation of the antitrypanosomal activity of buchholzia coriacea seed extract against a field strain of trypanosoma congolense. Pdf protective effects of buchholzia coriacea seeds extract and. The board of trustees of the royal botanic gardens, kew. The phytochemicals obtained from both water and methanolic extracts of dried seed were alkaloids, tannins, flavonoids, saponins, cardiac glycosides, glycosides. Please note that this is a trial program and may end. Umeokoli blessing ogechukwu 1, abba chika 1, ezeh peter 2, ajaghaku daniel 3, onyegbule felix afamefule 1.
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